While Ivermectin has been shown to promote cancer cell death at controlled doses, researchers are yet to resolve a few key issues. In this episode, we will explore why researchers believe Ivermectin to turn into a potential anti-cancer medicine.
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Ivermectin has been in use because it has a strong effect on parasites. However, the latest research shows that Ivermectin (IVM) has potential anti-viral effects—important in the treatment of cancer.
What is Ivermectin or IVM?
A macrolide antiparasitic drug, IVM has a 16-membered ring that is generally effective in the treatment of parasitic diseases such as elephantiasis, scabies, and river blindness. In 2015, Satoshi ōmura and William C. Campbell won the Nobel Prize in Medicine for the discovery of the effectiveness of IVM against parasitic diseases.
As per the latest findings, IVM is reported to curb the proliferation of tumor cells, making it an excellent candidate for it being used as an anticancer drug.
Erin Elizabeth, a journalist with years of experience, recently took to her Twitter handle to mention the following:
“We love this awesome doctor from Harvard who explains that ivermectin is actually getting people better from cancer. That’s why they don’t want you to know about it and they call it horse paste. It’s given to tens of millions of people every month.”
She shared the link of a video along with the Tweet.
An article published on ScienceDirect mentions the following:
“Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase… Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance and exerts the optimal effect when used in combination with other chemotherapy drugs.”
While there have been a large number of studies on the efficacy of IVM in the treatment of cancer, there are still some key issues to be resolved. First, the mechanism through which IVM mediates cytotoxicity in tumor cells is vague. Second, IVM has been found to induce mixed cell deaths in tumor cells.
While researchers are continuing their efforts on a breakthrough, IVM has shown efficacy on different types of cancer such as breast cancer, digestive system cancer, urinary system cancer, hematological cancer, reproductive system cancer, brain glioma, respiratory system cancer, and melanoma.
We will talk about the efficacy of Ivermectin in other episodes.
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