Why Checkpoint Inhibitors are the Next Level of Cancer Treatment
Immune checkpoints form part of the immune system and prevent the immune response from being excessively strong so that it does not destroy healthy cells. In this episode, we will explore how immune checkpoint inhibitors work in fighting cancerous cells.
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Cancer cells disguise themselves and bind with T cells; however, immune checkpoints fail to recognize cancer cells, resulting in cancer growth. Immune checkpoint inhibitors help T cells recognize cancerous cells and assist them to fight it.
Immunotherapy is truly the next level in cancer treatment. It works with the body’s immune system to fight cancer. Immune checkpoint inhibitors are immunotherapy drugs that are administered to cancer patients, allowing them to fight cancer effectively.
An article published by the National Cancer Institute mentions the following:
“Immunotherapy drugs called immune checkpoint inhibitors work by blocking checkpoint proteins from binding with their partner proteins. This prevents the “off” signal from being sent, allowing the T cells to kill cancer cells.”
What are checkpoint inhibitors?
Simply put, it is a type of immunotherapy that blocks proteins that stop the immune system from recognizing cancer cells. To learn more about immunotherapy, click the link in the description.
How do checkpoint inhibitors work?
Our immune system is one of the most powerful weapons against bacteria and viruses. T cells are part of the immune system that has a major role to play in fighting deadly diseases. T cells are governed by a protein that binds with them. These proteins trigger immune responses when fighting life-threatening diseases; however, T cells fail to recognize cancer cells because they disguise themselves as healthy cells. Checkpoint inhibitors block those proteins that turn off T cells from recognizing cancer cells.
Different types of cancers treated with checkpoint inhibitors
While checkpoint inhibitors are the next level in cancer treatment, not every type of cancer can be treated using them. Some types of cancers that can be treated using checkpoint inhibitors are as follows:
- Rectal cancer
- Breast cancer
- Colon cancer
- Cervical cancer
- Bladder cancer
- Hodgkin lymphoma
- Lung cancer
- Liver cancer
- Renal cell cancer
- Stomach cancer
- Skin cancer
- Any type of solid tumor
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